111

Mass-selective and ice-free cryo-EM protein sample preparation via native electro spray ion-beam deposition.
Esser, T.K., Böhning, K., Fremdling, P., Agasid, M.T., Costin, A., Fort, K., Konijnenberg, A., Gilbert, J.D., Bahm, A., Makarov, A., Robinson, C.V., Benesch, J.L.P., Baker, L., Bharat, T.A.M., Gault, J., Rauschenbach, S.
PNAS Nexus, (2022), 1 (4): pgac153
Download from publisher website

110

Complementing machine learning-based structure predictions with native mass spectrometry
Allison, T.M., Degiacomi, M.T., Marklund, E.G., Jovine, L., Elofsson, A., Benesch, J.L.P., Landreh, M.
Protein Science, (2022), 31 (6): e4333
Download from publisher website

109

Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent responses
Meng, J.X., Zhang, Y., Saman, D., Haider, A.M., De, S., Sang, J.S., Brown, K., Jiang, K., Humphrey, J., Julian, L., Hidari, E., Lee, S.F., Balmus, G., Floto, R.A., Bryant, C.E., Benesch, J.L.P., Ye, Y., Klenerman, D. Nature Communications, (2022), 13: 2692
Download from publisher website

108

Shape-morphing of an artificial protein cage with unusual geometry induced by a single amino acid change
Sharma, M., Biela, A.P., Kowalcyk, A., Borzecka-Solarz, K., Piette, P.M.A.G., Gawel, S., Bishop, J., Kukura, P., Benesch, J.L.P., Imamura, M. Scheuring, S., Heddle, J.G.
ACS Nano, (2022)
Download from publisher website

107

Biobox: A toolbox for biomolecular modelling
Rudden, S.P.lL., Musson, S.M., Benesch, J.L.P., Degiacomi, M.T
Bioinformatics, (2021), 38(4): 1149-1151
Download from publication website

106

Charge Engineering Reveals the Roles of Ionizable Side Chains in Eletrospray Ionization Mass Spectrometry
Abramsson, M.L., Sahin, C., Hopper, T.S., Branca, R.M.M., Danielsson, J., Xu, M., Chandler, S.A., Westerlund, N., Ilag, L.L., Leppert, A., Costeira-Paulo, J., Lang, L., Teilum, K., Laganoswky, A., Benesch, J.L.P., Oliveberg, M., Robinson, C.V., Marklund, E.G., Allison, T.M., Winther, J.R., Landreh, M.
JACS Au 2021
Download from publication website

105

Chaperones: Aggregation in the spotlight
Wang, Z., Collier, M., Benesch, J.L.P.
eLife, (2021), e73586
Download from publication website

104

The binding of the small heat-shock protein aB-crystallin to fibrils of a-synuclein is driven by entropic forces
Scheidt, T., Carozza, J.A., Kolbe, C.C., Aprile, F.A., Tkachenko O., Bellaiche M.M.J., Meisl, G., Peter, Q.A.E., Herling, T.W., Ness, S., Castellana-Cruz, M., Benesch, J.L.P., Vendruscolo, M., Dobson, C.M, Arosio, P., Knowles, T.P.J.
PNAS , (2021), 118 (38) e2108790118
Download from publication website

103

A weakened interface in the P182L variant of HSP27 associated with severe Charcot-Marie-Tooth neuropathy causes aberrant binding to interacting proteins.
Alderson, T.R., Adriaenssens, E., Asselbergh, B., Pritisanac, I., Van Lent, J., Gastall, H.Y., Waelti, M., Louis, J.M., Timmermann, V., Baldwin, A.J., Benesch, J.L.P.
EMBO J, (2021), e103811
Download from publication website
Also a pre-print on BioRxiv

102

Ion mobility-mass spectrometry shows stepwise protein unfolding under alkaline conditions.
Sahin, C., Westerlund, N., Leppert, A., Johansson, J., Marklund, E., Benesch, J.L.P., Slag, L.L., Allison, T.M., Landreh, M,
Chemical Communications, (2021)
Download

101

Single-molecule fluorescence-based approach reveals novel mechanistic insights into human small heat shock protein chaperone function.
Johnston, C.L, Marzano, N.R., Paudel, B.P., Wright, G., Benesch, J.L.P., Van Oijen, A.M., Ecroyd, H.
Journal of Biological Chemistry, (2020)
Download from the publication website

100

Software requirements for the analysis and interpretation of native ion mobility mass spectrometry data
Allison, T., Barran, P., Benesch, J.LP., Cianferani, S., Degiacomi, M., Gabelica, V., Grandori R., Marklund, E., Menneteau, T., Migas, L., Politis, A., Sharon, M., Sobott, F., Thalassinos, K.
Analytical Chemistry, (2020), 92(16): 110881-10890
Download

99

Computational strategies and challenges for using native ion mobility mass spectrometry in biophysics and structural biology
Allison, T., Barran, P., Cianferani, S., Degiacomi, M., Gabelica, V., Grandori R., Marklund, E., Menneteau, T., Migas, L., Politis, A., Sharon, M., Sobott, F., Thalassinos, K., Benesch, J.LP.
Analytical Chemistry, (2020), 92(16): 10872-10880
Download

98

Origins of complexity in haemoglobin evolution
Pillai, A.S., Chandler, S.A., Liu, Y., Signore, A.V., Cortez-Romero, C.R., Benesch, J.L.P., Laganowsky, A., Storz, J.F., Hochberg, G.K.A., Thornton, J.W.
Nature, (2020), 581 (7809): 480-485
Download

97

Quantifying the heterogeneity of macromolecular machines by mass photometry
Sonn-Segev, A., Belacic, K., Bodrug, T., Young, G., VanderLinden R.T., Schulman, B.A., Schimpf, J., Friedrich, T., Vinh Dip, P., Schwartz, T.U., Bauer, B., Peters, J-M., Struwe, W.B., Benesch, J.L.P., Brown, N.G., Haselbach, D., Kukura, P.
Nature communications, (2020), 11(1): 1772
Download

96

Small heat-shock proteins and their role in mechanical stress
Collier, M.P., Benesch, J.L.P.
Cell Stress and Chaperones, (2020), 25: 601-613
Download

95

Screenshot 2020-10-20 at 10.35.09

Quantifying protein-protein interactions by molecular counting with mass photometry
Soltermann, F., Foley, E.D.B., Pagnoni, V., Galpin, M.R., Benesch, J.L.P., Kukura, P., Struwe, W.B.
Angewandte Chemie, (2020), 59 (27): 10774-10779
Download

94

Conditional disorder in small heat-shock proteins
Alderson, T.R., Ying, J., Bax, A., Benesch, J.L.P., Baldwin, AJ.
Journal of Molecular Biology, (2020), 432 (9): 3033-3049
Download

93

Monitoring protein-metal binding by 19F NMR - a case study with the New Delhi metallo-ß-lactamase 1 Rydzik, A., Brem, J., Chandler, S.A., Benesch, J.L.P., Claridge, T.D.W., Schofield, C.J.,
RSC Medicinal Chemistry, (2020), 11 (3): 387-391
Download

92

The trajectory taken by dimeric Cu/Zn superoxide dismutase through the protein unfolding and dissociation landscape is modulated by salt-bridge formation
McAlary, L., Harrison, J.A., Aquilina, J.A., Fitzgerald, S.P., Kelso, C., Benesch, J.L.P., Yerbury, J.J
Analytical Chemistry, (2020), 92 (2), 1702-1711
Download

91

αB-crystallin inhibits amyloidogenesis by disassembling aggregation nuclei
Tkachenko, O., Benesch, J.L.P., Baldwin, A.J.
BioRxiv

90

Analysis of αB-crystallin polydispersity in soluation through native micorfludicid electrophoresis
Wright, M.A., Ruggeri, F.S., Saar, K.L., Challa, P.K., Benesch, J.L.P., Knowles, T.P.J.
Analyst, (2019),144, 4413-4424
Download

89

HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C
Collier, M., Alderson, T.R., de Villiers, C., Nicholls, D., Gastall, H., Allison, T., Degiacomi, M., Fuerst, D., van de Ven, P., Djinovic-Carugo, K., Baldwin, A., Watkins, H., Gehmlich, K., Benesch, J.L.P.
Science Advances, (2019), 5, eeaav8421
Download
BioRxiv

88

An ultra-stable gold-coordinated protein cage displaying reversible assembly
Malay, A.D., Miyazaki, N., Biela, A., Chakraoborti, S., Majesterkiewicz, K., Stupka, I., Kaplan, C.S., Kowalczyk, A., Piette, B.M.A.G., Hochberg, G.K.A., Wu, D., Wrobel, T.P., Fineberg, A., Kushwah, M.S., Klemen, M., Vavpetic, P., Pelicon, P., Kukura, P., Benesch, J.L.P., Iwasaki, K., Heddle, J.G.
Nature, (2019), 569, 438-42
Download

87

Local unfolding of the HSP27 monomer regulates chaperone activity
Alderson, T.R., Roche, J., Gastall, H.Y., Pritišanac, I., Ying, J., Bax, A., Benesch, J.L.P., Baldwin, A.J.
Nature Communications, (2019), 10, 1068
Download
BioRxiv doi:10.1101/345751

86

jbc_ryan_cover
Structural and Functional Consequences of Age-Related Isomerization in α Crystallins
Lyon, Y., Collier, M.P, Riggs, D., Degiacomi, M.T, Benesch, J.L.P, Julian, R.
Journal of Biological Chemistry, (2019), 294,7546-55
Download
BioRxiv

85

Small heat shock proteins: multifaceted proteins with important implications for life
Carra, S., Albert, S., Benesch J.L.P., Boelens, W., Buchner, J., Carver, J.A., Cecconi, C., Ecroyd, H., Gusev, N., Hightower, L.E., Klevit, R.E., Lee, H.O., Liberek, K., Lockwood, B., Poletti, A., Timmerman, V., Toth, M.E., Vierling, E., Wu, T., Tanguay, R.M.
Cell Stress Chaperones (2019), 24, 295-308
Download

84

X0959440X
Weighing-up protein dynamics: the combination of native mass spectrometry and molecular dynamics simulations
Marklund, E.G., Benesch, J.L.P.
Current Opinion in Structural Biology, (2019), 54, 50-8
Download

83

Recommendations for reporting ion mobility mass spectrometry measurements
Gablica, V., Shvartsburg, A.A., Afonso, C., Barran, P.E., Benesch, J.L.P., Bleiholder, C., Bowers, M., Bilbao, A., Bush, M.F., Campbell, J.L., Campuzano, I.D.G., Causon, T.J., Clowers, B.H., Creaser, C., De Pauw, E., Far, J., Fernandez-Lima, F., Fjelsted, J.C., Giles, K., Groessl, M., Hogan, C.J.Jr., Hann, S., Kim, H.I., Kurulugama, R.T., May, J.C., McLean, J.A., Pagel, K., Richardson, K., Ridgeway, M.E., Rosu, F., Sobott, F., Thalassinos, K., Valentine, S.J., Wyttenbach, T.
Mass Spectrometry Reviews, (2019), 38, 291-320
Download
ChemRXiv

82

Probing the dissociation of protein complexes by means of gas-phase H/D exchange mass spectrometry
Mistarz, U.H. , Chandler, S.A., Brown, J.M., Benesch, J.L.P., Rand, K.D.
Journal of the American Society for Mass Spectrometry, (2019), 30, 45-57
Download

81

JBC_cover
It takes a dimer to tango: Oligomeric small heat-shock proteins dissociate to capture substrate
Santhanagopalan, I., Degiacomi, M.T., Sheperd, D.A., Hochberg, G.K.A., Benesch, J.L.P., Vierling, E.
Journal of Biological Chemistry, (2018), 293, 19511-21
Download
bioRxiv

80

Terminal regions confer plasticity to the tetrameric assembly of human HspB2 and HspB3
Clark, A.R., Egberts, W.V., Kondrat, F.D.L., Hilton, G.R., Ray, N.J., Cole, A.R., Carver, J.A., Benesch, J.L.P., Keep, N.H., Boelens, W.C., Slingsby, C.
J. Mol. Biol. (2018) , 430 (18), Part B, 3297-3310
Download from the publishers website

79

Engineering of a Polydisperse Small Heat-Shock Protein Reveals Conserved Motifs of Oligomer Plasticity
Mishra, S., Chandler, S.A., Williams, D., Claxton, D.P., Koteiche, H.A., Stewart, P.L., Benesch, J.L.P., Mchaourab, H.S.
Structure (2018)
BioRxiv
Download via the publisher's website

78

The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases
Markolovic, S., Zhuang, Q., Wilkins, S.E., Eaton, C.D., Abboud, M., Katz, M.J., McNeil, H.E., LeĊ›niak, R., Hall, C., Struwe, W.B., Konietzny, R., Davis, S., Yang, M., Ge, W., Benesch, J., Kessler, B., Ratcliffe, P., Cockman, M., Fischer, R., Wappner, P., Chowdhury, R., Coleman, M., Schofield, C.J.
Nat. Chem. Biol. (2018), 14, 688-695

Download
Correction

77

Lipid binding attenuates channel closure of the outer membrane protein OmpF
Liko, I., Degiacomi, M.T., Lee, S., Newport, T.D., Gault, J., Reading, E., Hopper, J.T.S., Housden, N.G., White, P., Colledge, M., Sula, A., Wallace, B.A., Kleanthous, C., Stansfeld, P.J., Bayley, H., Benesch, J.L.P., Allison, T.M., and Robinson, C.V.
PNAS (2018), 115 (26), 6691-6696
Download

76

Identifying key membrane protein lipid interactions using mass spectrometry.
Gupta K, Li J, Liko I, Gault J, Bechara C, Wu D, Hopper JTS, Giles K, Benesch JLP, Robinson CV.
Nat. Protoc. (2018) 13 (5), 1106-1120

Download via the publisher's website

75

Quantitative mass imaging of single biological macromolecules
Young, G., Hundt, N., Cole, D., Fineberg, A., Andrecka, J., Tyler, A., Olerinyova, A., Ansari, A., Marklund, E.G., Collier, M.P., Chandler, S.A., Tkachenko, O., Allen, J., Crispin, M., Billington, N., Takagi, Y., Sellers, J.R., Eichmann, C., Selenko, P., Frey, L., Riek, R., Galpin, M.R., Struwe, W.B., Benesch, J.L.P., Kukura, P.
Science (2018) 360 (6387), 423-427

Download
Data
BioRxiv

74

The influence of the N-terminal region proximal to the core domain on the assembly and chaperone activity of αB-crystallin
Jovcevski, B., Andrew Aquilina, J., Benesch, J.L.P., Ecroyd, H.
Cell Stress Chaperones (2018) doi:10.1007/s12192-018-0889-y

Download

73

Structural and functional aspects of the interaction partners of the small heat-shock protein in Synechocystis.
Marklund, E.G., Zhang, Y., Basha, E., Benesch, J.L.P., Vierling, E.
Cell Stress and Chaperones (2018) doi:10.1007/s12192-018-0884-3

Download
Correction via publisher's website

72

Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions
Hochberg, G.K.A., Shepherd, D.A., Marklund, E.G., Santhanagoplan, I., Degiacomi, M.T., Laganowsky, A., Allison, T.M., Basha, E., Marty, M.T., Galpin, M.R., Struwe, W.B., Baldwin, A.J., Vierling, E., Benesch, J.L.P.
Science (2018), 359 (6378), 930-935

Download
Data

71

Real-Time Intrinsic Fluorescence Visualization and Sizing of Proteins and Protein Complexes in Microfluidic Devices.
Challa, P.K., Peter, Q., Wright, M.A., Zhang, Y., Saar, K.L., Carozza, J.A., Benesch, J.L.P., Knowles, T.P.J.
Anal. Chem. (2018), 90 (6), 3849-3855

Download

70

Mass spectrometry beyond the native state
Chandler, S.A., Benesch, J.L.P.
Curr. Opin. Chem. Biol. (2017), 42, 130-137

Download

69

Evaluating the Effect of Phosphorylation on the Structure and Dynamics of Hsp27 Dimers by Means of Ion Mobility Mass Spectrometry
Jovcevski, B., Kelly, M.A., Aquilina, J.A., Benesch, J.L.P., Ecroyd, H
Anal. Chem. (2017), 89 (24), 13275-13282
Download

68

Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7
Gerken, P.A., Wolstenhulme, J.R., Tumber, A., Hatch, S.B., Zhang, Y., Müller, S., Chandler, S.A., Mair, B., Li, F., Nijman, S.M.B., Konietzny, R., Szommer, T., Yapp, C., Fedorov, O., Benesch, J.L.P., Vedadi, M., Kessler, B.M., Kawamura, A., Brennan, P.E., Smith, M.D.
Angew. Chem. (International ed. in English) (2017), 56 (49), 15555-15559
Download

67

Adenosine Monophosphate Binding Stabilizes the KTN Domain of the Shewanella denitrificans Kef Potassium Efflux System.
Pliotas, C., Grayer, S.C., Ekkerman, S., Chan, A.K.N., Healy, J., Marius, P., Bartlett, W., Khan, A., Cortopassi, W.A., Chandler, S.A., Rasmussen, T., Benesch, J.L.P., Paton, R.S., Claridge, T.D.W., Miller, S., Booth, I.R., Naismith, J.H., Conway, S.J.
Biochemistry (2017), 56 (32), 4219-4234

Download via the publisher's website

66

Accommodating protein dynamics in the modeling of chemical crosslinks
Degiacomi, MT, Schmidt, C, Baldwin, AJ, Benesch, JLP
Structure, (2017), 25, 1-7
Download

65

Controlling Protein Orientation in Vacuum Using Electric Fields
Marklund E.G., Ekeberg T., Moog M., Benesch J.L.P., Caleman C.
J. Phys. Chem. Lett., (2017), 8 (18), 4540-4544
Download

64

Proline isomerization in the C-terminal region of HSP27
Alderson, T.R., Benesch, J.L., Baldwin, A.J.
Cell Stress Chaperones (2017), 22, 639-651
Download

63

The growing world of small heat shock proteins: from structure to functions
Carra, S., Alberti, S., Arrigo, P.A., Benesch, J.L., Benjamin, I.J., Boelens, W., Bartelt-Kirbach, B., Brundel, B.J., Buchner, J., Bukau, B., Carver, J.A., Ecroyd, H., Emanuelsson, C., Finet, S., Golenhofen, N., Goloubinoff, P., Gusev, N., Haslbeck, M., Hightower, L.E., Kampinga, H.H., Klevit, R.E., Liberek, K., Mchaourab, H.S., McMenimen, K.A., Poletti, A., Quinlan, R., Strelkov, S.V., Toth, M.E., Vierling, E., Tanguay, R.M.
Cell Stress Chaperones (2017), 22 (4), 601-611
Download

62

The Tetrameric Plant Lectin BanLec Neutralizes HIV through Bidentate Binding to Specific Viral Glycans.
Hopper, J.T.S., Ambrose. S., Grant, O.C., Krumm, S.A., Allison, T.M., Degiacomi, M.T., Tully, M.D., Pritchard, L.K., Ozorowski, G., Ward, A.B., Crispin, M., Doores, K.J., Woods, R.J., Benesch, J.L.P., Robinson, C.V., Struwe, W.B.
Structure (2017), 25 (5), 773-782.e5
Download

61

Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters
Landreh, M., Marklund, E.G., Uzdavinys, P., Degiacomi, M.T., Coincon, M., Gault, J., Gupta, K., Liko, I., Benesch, J.L.P., Drew, D., Robinson, C.V.
Nat. Commun. (2017), 13993
Download

60

Protein aggregate-ligand binding assays based on microfluidic diffusional separation
Zhang, Y., Buell, A.K., Müller, T., Benesch, J.L.P., Dobson, C.M., Knowles, T.P.J.
ChemBioChem (2016), 17 (20), 1920–1924
Download

59

Infrared laser activation of soluble and membrane protein assemblies in the gas phase
Mikhailov, V.A., Liko, I., Mize, T.H., Bush, M.F., Benesch, J.L.P., Robinson, C.V.
Anal. Chem. (2016), 88(14), 7060-7
Download

58

The human 343delT HSPB5 chaperone associated with early-onset skeletal myopathy causes defects in protein solubility
Mitzelfelt, K.A., Limphong, P., Choi, M.J., Kondrat, F.D., Lai, S., Kolander, K.D., Kwok, W.M., Dai, Q., Grzybowski, M.N., Zhang, H., Taylor, G.M., Lui, Q., Thao, M.T., Hudson, J.A., Barresi, R., Bushby, K., Jungbluth, H., Wraige, E., Geurts, A.M., Benesch, J.L.P., Riedel, M., Christians, E.S., Minella, A.C., Benjamin, I.J.
J. Biol. Chem. (2016), 291(29), 14939-53
Download

57

Low charge and reduced mobility of membrane protein complexes has implications for calibration of collision cross section measurements
Allison, T.M., Landreh, M., Benesch, J.L.P, Robinson, C.V.
Anal. Chem. (2016), 88(11), 5879-84
Download

56

Negative ions enhance survival of membrane protein complexes
Liko, I, Hopper. J.T., Allison. T.M., Benesch, J.L.P., Robinson, C.V.
J. Am. Soc. Mass Spectrom. (2016), 27(6), 1099-104
Download

55

Characterisation of Shigella Spa33 and Thermotoga FliM/N reveals a new model for C-ring assembly in T3SS
McDowell, M.A., Marcoux, J., McVicker, G., Johnson, S., Fong, Y.H., Stevens, R., Bowman, L.A., Degiacomi, M.T., Yan, J., Wise, A., Friede, M., Benesch, J.L.P., Deane, J.E., Tang, C.M., Robinson, C.V., Lea, S.M.
Mol. Micro. (2016), 99, 759-66
Download via the publisher's website

54

GlycoMob: an ion mobility-mass spectrometry collision cross section database for glycomics
Struwe, W.B., Pagel, K., Benesch, J.L.P., Harvey, D.J., Campbell, M.P.
Glycoconj. J. (2016), 33, 399-404
Download via the publisher's website

53

Optimal synthetic glycosylation of a therapeutic antibody
Parsons, T.B., Struwe, W.B., Gault, J., Yamamoto, K., Taylor, T.A., Raj, R., Wals, K., Mohammed, S., Robinson, C.V., Benesch, J.L.P., Davis, B.G.
Angew. Chem. Int. Ed. (2016), 55, 2361-7
Download

52

EMIM: software for relating ion mobility mass spectrometry and electron microscopy data
Degiacomi, M.T., Benesch, J.L.P.
Analyst (2016), 141, 70-5
Download via publisher's website
website

51

A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis
Marcoux, J., Mangione, P.P., Porcari, R., Degiacomi, M.T., Verona, G., Taylor, G.W., Giorgetti, S., Raimondi, S., Sanglier-Cianférani, S., Benesch, J.L.P., Cecconi, C., Naqvi, M.M., Gillmore, J.D., Hawkins, P.N., Stoppini, M., Robinson, C.V., Pepys, M.B., Bellotti, V.
EMBO Mol. Med. (2015), 7, 1337-49
Download via the publisher's website
video

50

Collision cross sections of high-mannose N-glycans in commonly observed adduct states - identification of gas-phase conformers unique to [M-H]- ions
Struwe, W.B., Benesch, J.L.P., Harvey, D.J., Pagel, K.
Analyst (2015), 140, 6799-803
Download via the publisher's website

49

Dynamics-function relationships of the small heat-shock proteins
Hochberg, G.K.A. & Benesch, J.L.P.
Heat Shock Proteins (2015), 8, 87-100
Download via the publisher's website

48

Bayesian deconvolution of mass and ion mobility spectra: from binary interactions to polydisperse ensembles
Marty, M.T., Baldwin, A.J., Marklund, E.G., Hochberg, G.K.A., Benesch, J.L.P., & Robinson, C.V.
Anal. Chem. (2015), 87, 4370-6
Download via the publisher's website
video
website

47

Collision cross sections for structural proteomics
Marklund, E.G., Degiacomi, M.T., Robinson, C.V., Baldwin, A.J., & Benesch, J.L.P.
Structure (2015), 23, 791-9
Download via the publisher's website
software

46

The role of the detergent micelle in preserving the structure of membrane proteins in the gas phase
Reading, E., Liko, I., Allison, T.M., Benesch, J.L.P., Laganowsky, A., & Robinson, C.V.
Angew. Chem. Int. Ed. (2015), 54, 4577-81
Download via the publisher's website

45

Combining tandem mass spectrometry with ion mobility separation to determine the architecture of polydisperse proteins
Shepherd, D.A., Marty, M.T., Giles, K., Baldwin, A.J., & Benesch, J.L.P.
Int. J. Mass Spectrom. (2015), 377, 663-71
Download

44

Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1
Brem, J., Struwe, W.B., Rydzik, A.M., Tarhonskaya, H., Pfeffer, I., Flashman, E., van Berkel, S.S., Spencer, J., Claridge, T.D.W., McDonough, M.A., Benesch, J.L.P., & Schofield, C.J.
Chem. Sci. (2015), 6, 956-63
Download via publisher's website

43

Phosphomimics destabilise HSP27 oligomeric assemblies and enhance chaperone activity
Jovcevski, B., Kelly, M.A., Rote, A.P., Berg, T., Gastall, H.Y., Benesch, J.L.P., Aquilina, J.A. & Ecroyd, H.
Chem. Biol. (2015), 22, 186-95
Download via publisher's website.

42

Native mass spectrometry: towards high-throughput structural proteomics
Kondrat, F.D., Struwe, W.B., & Benesch, J.L.P.
Methods Mol. Biol. (2014), 1261, 349-71
Download

41

Ejection of structural zinc leads to inhibition of γ-butyrobetaine hydroxylase
Rydzik, A.M., Brem, J., Struwe, W.B., Kochan, G.T., Benesch, J.L.P., & Schofield C.J.
Bioorg. Med. Chem. Lett. (2014), 24, 4954-7
Download

40

Mass-selective soft-landing of protein assemblies with controlled landing energies
Mikhailov, V.A., Mize, T.H., Benesch, J.L.P., & Robinson, C.V.
Anal. Chem. (2014), 86, 8321-8
Download

39

Dynamical structure of αB-crystallin
Hochberg, G.K.A. & Benesch, J.L.P.
Prog. Biophys. Mol. Biol. (2014), 115, 11-20
Download

38

The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity
Hochberg, G.K.A, Ecroyd, H., Liu, C., Cox, D., Cascio, D., Sawaya, M.R., Collier, M.P., Stroud, J., Carver, J.A., Baldwin, A.J., Robinson, C.V., Eisenberg, D.S., Benesch, J.L.P. & Laganowsky, A.
Proc. Natl. Acad. Sci. U.S.A. (2014), 111, E1562-70
Download
commentary

37

2013 Detergent-Free Mass Spectrometry of Membrane Protein Complexes - Cover
Detergent-free mass spectrometry of membrane protein complexes
Hopper, J.T., Yu, Y.T., Li, D., Raymond, A., Bostock, M., Liko, I., Mikhailov, V., Laganowsky, A., Benesch, J.L.P., Caffrey, M., Nietlispach, D., & Robinson, C.V.
Nat. Methods (2013), 10, 1206-8
Download
cover

36

HSP70 oligomerization is mediated by an interaction between the interdomain linker and the substrate binding domain
Aprile, F.A., Dhulesia, A., Stengel, F., Roodveldt, C., Benesch, J.L.P., Tortora, P., Robinson, C.V., Salvatella, X., Dobson, C.M., & Cremades, N.
PLOS One (2013), 8, e6796
Download

35

C-terminal interactions mediate the quaternary dynamics of αB-crystallin
Hilton, G.R., Hochberg, G.K.A., Laganowsky, A., McGinnigle, S.I., Baldwin, A.J., & Benesch, J.L.P.
Phil. Trans. Roy. Soc. B (2013), 368, 20110405
Download

34

Probing dynamic conformations of the high molecular weight αB-crystallin heat shock protein ensemble by NMR spectroscopy
Baldwin, A.J., Walsh, P., Hansen, D.F., Hilton, G.R., Benesch, J.L.P., Sharpe, S., & Kay, L.E.
J. Am. Chem. Soc. (2012), 134, 15343-50
Download

33

The unusual mycobacterial chaperonins: Evidence for in vivo oligomerization and specialization of function
Fan, M., Rao, T., Zacco, E., Ahmed, M.T., Shukla, A., Ojha, A., Freeke, J., Robinson, C.V., Benesch, J.L.P., & Lund, P.A..
Mol. Micro. (2012), 85, 934-33
Download

32

Dissecting heterogeneous molecular chaperone complexes using a mass spectrum deconvolution approach
Stengel, F., Baldwin, A.J., Bush, M.F., Hilton, G.R., Lioe, H., Basha, E., Jaya, N., Vierling, E. & Benesch, J.L.P.
Chem & Biol. (2012), 19, 599-607
Download
commentary

31

Small heat-shock proteins: paramedics of the cell
Hilton, G.R., Lioe, H., Stengel, F., Baldwin, A.J. & Benesch, J.L.P.
Top. Curr. Chem. (2012), 328, 69-98
Download

30

Two decades of studying non-covalent biomolecular assemblies by means of electrospray ionisation mass spectrometry
Hilton, G.R. & Benesch, J.L.P.
J. R. Soc. Interface (2012), 9, 801-16
Download

29

The polydispersity of αB-crystallin is rationalised by an interconverting polyhedral architecture
Baldwin A.J., Lioe, H., Hilton, G.R., Baker, L.A., Rubinstein, J.L., Kay, L.E. & Benesch, J.L.P.
Structure (2011), 19, 1855-63
Download

28

Mass spectrometry: come of age for structural and dynamical biology
Benesch, J.L.P. & Ruotolo, B.T.
Curr. Op. Struc. Biol. (2011), 21, 641-9
Download

27

Quaternary dynamics of αB-crystallin as a direct consequence of localised tertiary fluctuations in the C-terminus
Baldwin A.J., Hilton, G.R., Lioe, H., Bagnéris, C., Benesch, J.L.P. & Kay, L.E.
J. Mol. Biol. (2011), 413, 310-20
Download
cover
commentary

26

αB-crystallin polydispersity is a consequence of unbiased quaternary dynamics
Baldwin A.J., Lioe, H., Robinson, C.V., Kay, L.E. & Benesch, J.L.P.
J. Mol. Biol. (2011), 413, 297-309
Download
cover
commentary

25

The quaternary organization and dynamics of the molecular chaperone HSP26 are thermally regulated
Benesch, J.L.P., Aquilina, J.A., Baldwin, A.J., Rekas, A., Stengel, F., Lindner, R., Basha, E., Devlin, G., Horwitz, J., Vierling, E., Carver, J.A. & Robinson, C.V.
Chem. Biol. (2010), 17, 1008-17
Download

24

Separating and visualising protein assemblies by means of preparative mass spectrometry and microscopy
Benesch, J.L.P., Ruotolo, B.T., Simmons, D.A., Barrera, N.P., Morgner, N., Wang, L., Saibil, H.R. & Robinson, C.V..
J. Struct. Biol. (2010), 172, 161-8
Download

23

Crystal structures of truncated αA and αB crystallins reveals structural mechanisms of polydispersity important for eye lens function
Laganowsky, A., Benesch, J.L.P., Landau, M., Ding, L., Sawaya, M.R., Cascio, D. Huang, Q., Robinson, C.V., Horwitz, J. & Eisenberg, D.
Protein Sci. (2010), 19, 1031-43
Download
cover

22

Quaternary dynamics and plasticity underlie small heat shock protein chaperone function
Stengel, F., Baldwin, A.J., Painter, A.J., Jaya, N., Basha, E., Kay, L.E., Vierling, E., Robinson, C.V. & Benesch, J.L.P.
Proc. Natl. Acad. Sci. U.S.A. (2010), 107, 2007-12
Download
commentary

21

Dehydrated but unharmed
Benesch, J.L.P. & Robinson, C.V.
Nature (2009), 462, 576-7
Download

20

The small heat-shock proteins HSPB2 and HSPB3 form well-defined heterooligomers in a unique 3 to 1 subunit ratio
den Engelsman, J., Boros, S., Dankers, P.Y., Kamps, B., Vree Egberts, W.T., Bode, C.S., Lane, L.A., Aquilina, J.A., Benesch, J.L.P., Robinson, C.V., de Jong, W.W. & Boelens, W.C.
J. Mol. Biol. (2009), 393, 1022-32
Download

19

Defining the structural basis of human plasminogen binding by streptococcal surface enolase
Cork, A.J., Jergic, S., Hammerschmidt, S., Kobe, B., Pancholi, V., Benesch, J.L.P., Robinson, C.V., Dixon, N.E., Aquilina, J.A. & Walker, M.J.
J. Biol. Chem. (2009), 284, 17129-37
Download

18

Coupling microdroplet microreactors with mass spectrometry: reading the contents of single droplets online
Fidalgo, L.M., Whyte, G., Ruotolo, B.T., Benesch, J.L.P., Stengel, F., Abell, C., Robinson, C.V. & Huck, W.T.
Angew. Chem. Int. Ed. (2009), 48, 3665-8
Download
commentary

17

A Monte-Carlo approach for assessing the specificity of protein oligomers observed in nano-electrospray mass spectra
Lane, L.A., Ruotolo, B.T., Robinson, C.V., Favrin, G. & Benesch, J.L.P.
Int. J. Mass Spectrom. (2009), 283, 169-77
Download

16

Collisional activation of protein complexes: picking up the pieces
Benesch, J.L.P.
J. Am. Soc. Mass. Spectrom. (2009), 20, 341-8
Download
cover

15

Quadrupole-time-of-flight mass spectrometer modified for higher-energy dissociation reduced protein assemblies to peptide fragments
Benesch, J.L.P., Ruotolo, B.T., Sobott, F., Wildgoose, J., Gilbert, A., Bateman, R. & Robinson, C.V. & Aquilina, J.A.
Anal. Chem. (2009), 81, 1270-4
Download

14

Small heat shock protein activity is regulated by variable oligomeric substructure
Benesch, J.L.P., Ayoub, M., Robinson, C.V. & Aquilina, J.A.
J. Biol. Chem. (2008), 283, 28513-7
Download

13

Ion mobility mass spectrometry analysis of large protein complexes
Ruotolo, B.T., Benesch, J.L.P., Sandercock, A.M., Hyung, S.-J. & Robinson, C.V.
Nat. Prot. (2008), 3, 1139-52
Download

12

Real-time monitoring of protein complexes reveals their quaternary organization and dynamics
Painter, A.J., Jaya, N., Basha, E., Vierling, E., Robinson, C.V. & Benesch, J.L.P.
Chem. Biol. (2008), 15, 246-53
Download
commentary

11

Protein complexes in the gas phase: technology for structural genomics and proteomics
Benesch, J.L.P., Ruotolo, B.T., Simmons, D.A. & Robinson, C.V.
Chem. Rev. (2007), 107, 3544-67
Download
cover

10

Mimicking phosphorylation of αB-crystallin affects its chaperone activity
Ecroyd, H., Meehan, S., Horwitz, J., Aquilina, J.A., Benesch, J.L.P., Robinson, C.V., MacPhee, C.E. & Carver, J.A.
Biochemical J. (2007), 401, 129-41
Download

9

Tandem mass spectrometry reveals the quaternary organization of macromolecular assemblies
Benesch, J.L.P., Aquilina, J.A., Ruotolo, B.T., Sobott, F. & Robinson, C.V.
Chem. Biol. (2006), 13, 597-605
Download

8

All three chaperonin genes in the archaeon Haloferax volcanii are individually dispensable
Kapatai, G., Large, A., Benesch, J.L.P., Robinson, C.V., Carrascosa, J.L., Valpuesta, J.M., Gowrinathan, P. & Lund, P.A.
Mol. Micro. (2006), 61, 1583-97
Download

7

Mass spectrometry of macromolecular assemblies: preservation and dissociation
Benesch, J.L.P. & Robinson, C.V.
Curr. Op. Struc. Biol. (2006), 16, 245-51
Download

6

Dodecameric structure of the small heat shock protein Acr1 from Mycobacterium tuberculosis
Kennaway, C., Benesch, J.L.P., Gohlke, U., Wang, L., Robinson, C.V., Orlova, E.V., Saibil, H.R. & Keep, N.H.
J. Biol. Chem. (2005), 280, 33419-35
Download
erratum
cover

5

Subunit exchange of polydisperse proteins: mass spectrometry reveals consequences of αA-crystallin truncation
Aquilina, J.A., Benesch, J.L.P., Ding, L.L., Yaron, O., Horwitz, J. & Robinson, C.V.
J. Biol. Chem. (2005), 280, 14485-91
Download

4

Phosphorylation of αB-crystallin alters chaperone function through loss of dimeric substructure
Aquilina, J.A., Benesch, J.L.P., Ding, L.L., Yaron, O., Horwitz, J. & Robinson, C.V.
J. Biol. Chem. (2004), 279, 28675-80
Download

3

Polydispersity of a mammalian chaperone: mass spectrometry reveals the population of oligomers in αB-crystallin
Aquilina, J.A., Benesch, J.L.P., Bateman, O.A., Slingsby, C. & Robinson, C.V.
Proc. Natl. Acad. Sci. U.S.A. (2003), 100, 10611-6
Download

2

Thermal dissociation of multimeric protein complexes by using nanoelectrospray mass spectrometry
Benesch, J.L.P., Sobott, F. & Robinson, C.V.
Anal. Chem. (2003), 75, 2208-14
Download
commentary
cover

1

Subunit exchange of multimeric protein complexes: real-time monitoring of subunit exchange between small heat shock proteins by using electrospray mass spectrometry
Sobott, F., Benesch, J.L.P., Vierling, E. & Robinson, C.V.
J. Biol. Chem. (2002), 277, 38921-9
Download